Neonates and infants are susceptible to skin barrier disruption since their skin is still developing anatomically and functionally. Skin acidification has a vital role in barrier maturation and the activation of enzymes involved in the extracellular processing of stratum corneum lipids. The present consensus paper investigated the challenges, and current treatment approaches in neonatal and infant normal and sensitive skin and the role of moisturizers with ceramides.

It conducted a discussion among an expert panel of pediatric dermatologists and dermatologists who amalgamated information from systematic literature, expert opinion, and experience of the panel to adopt eight statements. 

They recommended that-

• Since the neonatal and infant skin remains more permeable to topical agents during the first years after birth, we must exercise particular caution with topical skincare regimens.
• Mildly acidic or pH-neutral cleansers benefit neonates′ and infants′ skin.
• Skincare for neonates and infants should be safe, effective, fragrance-free, and sensitizing agent-free.
• The skincare should be pleasant to use, including ingredients that benefit the lipid and water content of the stratum corneum, like products containing ceramides.

Considering the maturation process of neonatal and infant skin, applying moisturizers and cleansers containing barrier lipids may help maintain the protective skin barrier and comfort with long-term moisturizing effects.

Schachner LA, Andriessen A, Benjamin L, et al.  A Consensus about the Importance of Ceramide Containing Skincare for Normal and Sensitive Skin Conditions in Neonates and Infants. J Drugs Dermatol. 2020;19(8) 769-776: doi:10.36849/JDD.2020.5252